Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems

PURPOSE: Histone deacetylase (HDAC) inhibition causes transcriptional activation or repression of several genes that in turn can influence the biodistribution of other chemotherapeutic agents. Here, we hypothesize that the combination of vorinostat, a HDAC inhibitor, with (131)I-metaiodobenzylguanid...

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Bibliografski detalji
Glavni autori: More, Swati S., Itsara, Melissa, Yang, Xiaodong, Geier, Ethan G., Tadano, Michelle K., Seo, Youngho, VanBrocklin, Henry F., Weiss, William A., Mueller, Sabine, Haas-Kogan, Daphne A., DuBois, Steven G., Matthay, Katherine K., Giacomini, Kathleen M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247296/
https://ncbi.nlm.nih.gov/pubmed/21421857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2949
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