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Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems

PURPOSE: Histone deacetylase (HDAC) inhibition causes transcriptional activation or repression of several genes that in turn can influence the biodistribution of other chemotherapeutic agents. Here, we hypothesize that the combination of vorinostat, a HDAC inhibitor, with (131)I-metaiodobenzylguanid...

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書誌詳細
主要な著者: More, Swati S., Itsara, Melissa, Yang, Xiaodong, Geier, Ethan G., Tadano, Michelle K., Seo, Youngho, VanBrocklin, Henry F., Weiss, William A., Mueller, Sabine, Haas-Kogan, Daphne A., DuBois, Steven G., Matthay, Katherine K., Giacomini, Kathleen M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247296/
https://ncbi.nlm.nih.gov/pubmed/21421857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2949
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