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Mechanotransduction In Vivo by Repeated Talin Stretch-Relaxation Events Depends upon Vinculin

Mechanotransduction is a critical function for cells, in terms of cell viability, shaping of tissues, and cellular behavior. In vitro, cellular level forces can stretch adhesion proteins that link extracellular matrix to the actin cytoskeleton exposing hidden binding sites. However, there is no evid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Margadant, Felix, Chew, Li Li, Hu, Xian, Yu, Hanry, Bate, Neil, Zhang, Xian, Sheetz, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243729/
https://ncbi.nlm.nih.gov/pubmed/22205879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001223
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