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Receptor Binding Enables Botulinum Neurotoxin B to Sense Low pH for Translocation Channel Assembly
Botulinum neurotoxins (BoNTs, serotypes A-G), elaborated by Clostridium botulinum, can induce lethal paralysis and are classified as category-A bioterrorism agents. However, how BoNTs translocate from endosomes into the cytosol of neurons to gain access to their intracellular targets remains enigmat...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243646/ https://ncbi.nlm.nih.gov/pubmed/21925111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.06.012 |
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