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Dendrimer-based Multivalent Methotrexates as Dual Acting Nanoconjugates for Cancer Cell Targeting

Cancer-targeting drug delivery can be based on the rational design of a therapeutic platform. This approach is typically achieved by the functionalization of a nanoparticle with two distinct types of molecules, a targeting ligand specific for a cancer cell, and a cytotoxic molecule to kill the cell....

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Autores principales: Li, Ming-Hsin, Choi, Seok Ki, Thomas, Thommey P., Desai, Ankur, Lee, Kyung-Hoon, Kotlyar, Alina, Banaszak Holl, Mark M., Baker, James R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243070/
https://ncbi.nlm.nih.gov/pubmed/22142685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.11.027
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