Protein Kinase C η is Required for T Cell Activation and Homeostatic Proliferation

Protein kinase Cη (PKCη) is highly abundant in T cells and is recruited to the immunological synapse that is formed between a T cell and a cognate antigen-presenting cell; however, its function in T cells is unknown. Here, we showed that PKCη was required for the activation of mature CD8(+) T cells...

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Hauptverfasser: Fu, Guo, Hu, Jianfang, Niederberger-Magnenat, Nathalie, Rybakin, Vasily, Casas, Javier, Yachi, Pia P., Feldstein, Stephanie, Ma, Bo, Hoerter, John A. H., Ampudia, Jeanette, Rigaud, Stephanie, Lambolez, Florence, Gavin, Amanda L., Sauer, Karsten, Cheroutre, Hilde, Gascoigne, Nicholas R. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242502/
https://ncbi.nlm.nih.gov/pubmed/22155788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002058
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