IP(3) 3-kinase B prevents bone marrow failure

Por Rigaud, Stephanie, Sauer, Karsten
Publicado no Oncotarget (2015)

A Conserved Motif in the ITK PH-Domain Is Required for Phosphoinositide Binding and TCR Signaling but Dispensable for Adaptor Protein Interactions

Por Hirve, Nupura, Levytskyy, Roman M., Rigaud, Stephanie, Guimond, David M., Zal, Tomasz, Sauer, Karsten, Tsoukas, Constantine D.
Publicado em 2012

IP(3) 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice

Por Siegemund, Sabine, Rigaud, Stephanie, Conche, Claire, Broaten, Blake, Schaffer, Lana, Westernberg, Luise, Head, Steven Robert, Sauer, Karsten
Publicado no Blood (2015)

Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent

Por Westernberg, Luise, Conche, Claire, Huang, Yina Hsing, Rigaud, Stephanie, Deng, Yisong, Siegemund, Sabine, Mukherjee, Sayak, Nosaka, Lyn'Al, Das, Jayajit, Sauer, Karsten
Publicado no eLife (2016)

In Silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP(4) Mediated Feedbacks Increase Robustness

Por Mukherjee, Sayak, Rigaud, Stephanie, Seok, Sang-Cheol, Fu, Guo, Prochenka, Agnieszka, Dworkin, Michael, Gascoigne, Nicholas R. J., Vieland, Veronica J., Sauer, Karsten, Das, Jayajit
Publicado em 2013

Correction: In Silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP(4) Mediated Feedbacks Increase Robustness

Por Mukherjee, Sayak, Rigaud, Stephanie, Seok, Sang-Cheol, Fu, Guo, Prochenka, Agnieszka, Dworkin, Michael, Gascoigne, Nicholas R. J., Vieland, Veronica J., Sauer, Karsten, Das, Jayajit
Publicado em 2014

Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling

Por Sauer, Karsten, Park, Eugene, Siegemund, Sabine, French, Anthony R., Wahle, Joseph A., Sternberg, Luise, Rigaud, Stephanie, Jonsson, A. Helena, Yokoyama, Wayne M., Huang, Yina H.
Publicado em 2013

Themis sets the signal threshold for positive and negative selection in T-cell development

Por Fu, Guo, Casas, Javier, Rigaud, Stephanie, Rybakin, Vasily, Lambolez, Florence, Brzostek, Joanna, Hoerter, John A.H., Paster, Wolfgang, Acuto, Oreste, Cheroutre, Hilde, Sauer, Karsten, Gascoigne, Nicholas R.J.
Publicado em 2013

CRISPR-Cas9–Mediated Modification of the NOD Mouse Genome With Ptpn22(R619W) Mutation Increases Autoimmune Diabetes

Por Lin, Xiaotian, Pelletier, Stephane, Gingras, Sebastien, Rigaud, Stephanie, Maine, Christian J., Marquardt, Kristi, Dai, Yang D., Sauer, Karsten, Rodriguez, Alberto R., Martin, Greg, Kupriyanov, Sergey, Jiang, Ling, Yu, Liping, Green, Douglas R., Sherman, Linda A.
Publicado no Diabetes (2016)

Protein Kinase C η is Required for T Cell Activation and Homeostatic Proliferation

Por Fu, Guo, Hu, Jianfang, Niederberger-Magnenat, Nathalie, Rybakin, Vasily, Casas, Javier, Yachi, Pia P., Feldstein, Stephanie, Ma, Bo, Hoerter, John A. H., Ampudia, Jeanette, Rigaud, Stephanie, Lambolez, Florence, Gavin, Amanda L., Sauer, Karsten, Cheroutre, Hilde, Gascoigne, Nicholas R. J.
Publicado em 2011