Lysophosphatidic Acid Signaling Protects Pulmonary Vasculature from Hypoxia-induced Remodeling

OBJECTIVE: Lysophosphatidic acid (LPA) is a bioactive lipid molecule produced by the plasma lysophospholipase D (lysoPLD) enzyme autotaxin that is present at ≥ 100 nM in plasma. Local administration of LPA promotes systemic arterial remodeling in rodents. To determine if LPA contributes to remodelin...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Cheng, Hsin-Yuan, Dong, Anping, Panchatcharam, Manikandan, Mueller, Paul, Yang, Fanmuyi, Li, Zhenyu, Mills, Gordon, Chun, Jerold, Morris, Andrew J., Smyth, Susan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241874/
https://ncbi.nlm.nih.gov/pubmed/22015657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.234708
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi