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Lysophosphatidic Acid Signaling Protects Pulmonary Vasculature from Hypoxia-induced Remodeling
OBJECTIVE: Lysophosphatidic acid (LPA) is a bioactive lipid molecule produced by the plasma lysophospholipase D (lysoPLD) enzyme autotaxin that is present at ≥ 100 nM in plasma. Local administration of LPA promotes systemic arterial remodeling in rodents. To determine if LPA contributes to remodelin...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241874/ https://ncbi.nlm.nih.gov/pubmed/22015657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.234708 |
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