Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses, but not blood pressure

Phenotypic modulation of vascular smooth muscle cells (SMC) is essential for the development of intimal hyperplasia. Lysophosphatidic acid (LPA) is a serum component that can promote phenotypic modulation of cultured SMC, but an endogenous role for this bioactive lipid as a regulator of SMC function...

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Detalhes bibliográficos
Main Authors: Panchatcharam, Manikandan, Miriyala, Sumitra, Yang, Fanmuyi, Rojas, Mauricio, End, Christopher, Vallant, Christopher, Dong, Anping, Lynch, Kevin, Chun, Jerold, Morris, Andrew J., Smyth, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637300/
https://ncbi.nlm.nih.gov/pubmed/18703779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.180778
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