Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice

Lysophosphatidic acid (LPA) is a bioactive lipid mediator. Concentrations of the major LPA species in mouse plasma decreased uniformly following administration of a potent selective inhibitor of the LPA-generating lysophospholipase D autotaxin, identifying an active mechanism for removal of LPA from...

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Main Authors: Salous, Abdel K., Panchatcharam, Manikandan, Sunkara, Manjula, Mueller, Paul, Dong, Anping, Wang, Yuhuan, Graf, Gregory A., Smyth, Susan S., Morris, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2013
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770090/
https://ncbi.nlm.nih.gov/pubmed/23948545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039685
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