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Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia

RATIONALE: The lipid phosphate phosphatase 3 (LPP3) degrades bioactive lysophospholipids including lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) and thereby terminates their signaling effects. While emerging evidence links LPA to atherosclerosis and vascular injury responses, little...

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Autors principals: Panchatcharam, Manikandan, Miriyala, Sumitra, Salous, Abdelghaffar, Wheeler, Jessica, Dong, Anping, Mueller, Paul, Sunkara, Manjula, Escalante-Alcalde, Diana, Morris, Andrew J., Smyth, Susan S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524385/
https://ncbi.nlm.nih.gov/pubmed/23104851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300527
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