Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas

Intraductal papillary mucinous neoplasm (IPMN) is a common pancreatic cystic neoplasm that is often invasive and metastatic, resulting in a poor prognosis. Few molecular alterations unique to IPMN are known. We performed whole-exome sequencing for a primary IPMN tissue, which uncovered somatic mutat...

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Hlavní autoři: Furukawa, Toru, Kuboki, Yuko, Tanji, Etsuko, Yoshida, Shoko, Hatori, Takashi, Yamamoto, Masakazu, Shibata, Noriyuki, Shimizu, Kyoko, Kamatani, Naoyuki, Shiratori, Keiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240977/
https://ncbi.nlm.nih.gov/pubmed/22355676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00161
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