Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) are the most common cystic precursor lesions of invasive pancreatic cancer. The recent identification of activating GNAS mutations at codon 201 in IPMNs is a promising target for early detection and therapy. The purpose of this study was t...

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Detalhes bibliográficos
Main Authors: Molin, Marco Dal, Matthaei, Hanno, Wu, Jian, Blackford, Amanda, Debeljak, Marija, Rezaee, Neda, Wolfgang, Christopher L., Butturini, Giovanni, Salvia, Roberto, Bassi, Claudio, Goggins, Michael G., Kinzler, Kenneth W., Vogelstein, Bert, Eshleman, James R., Hruban, Ralph H., Maitra, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842009/
https://ncbi.nlm.nih.gov/pubmed/23846778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-013-3096-1
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