Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) are the most common cystic precursor lesions of invasive pancreatic cancer. The recent identification of activating GNAS mutations at codon 201 in IPMNs is a promising target for early detection and therapy. The purpose of this study was t...

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Main Authors: Molin, Marco Dal, Matthaei, Hanno, Wu, Jian, Blackford, Amanda, Debeljak, Marija, Rezaee, Neda, Wolfgang, Christopher L., Butturini, Giovanni, Salvia, Roberto, Bassi, Claudio, Goggins, Michael G., Kinzler, Kenneth W., Vogelstein, Bert, Eshleman, James R., Hruban, Ralph H., Maitra, Anirban
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842009/
https://ncbi.nlm.nih.gov/pubmed/23846778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-013-3096-1
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