Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) are the most common cystic precursor lesions of invasive pancreatic cancer. The recent identification of activating GNAS mutations at codon 201 in IPMNs is a promising target for early detection and therapy. The purpose of this study was t...

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Autori principali: Molin, Marco Dal, Matthaei, Hanno, Wu, Jian, Blackford, Amanda, Debeljak, Marija, Rezaee, Neda, Wolfgang, Christopher L., Butturini, Giovanni, Salvia, Roberto, Bassi, Claudio, Goggins, Michael G., Kinzler, Kenneth W., Vogelstein, Bert, Eshleman, James R., Hruban, Ralph H., Maitra, Anirban
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842009/
https://ncbi.nlm.nih.gov/pubmed/23846778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-013-3096-1
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