Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

BACKGROUND: Pancreatic cancer is characterized by constitutive activation of mitogen-activated protein kinase (MAPK). Activation of MAPK is associated with the upregulation of genes implicated in the proliferation and survival of pancreatic cancer cells. We hypothesized that knockdown of these MAPK-...

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Detalhes bibliográficos
Main Authors: Furukawa, Toru, Tanji, Etsuko, Kuboki, Yuko, Hatori, Takashi, Yamamoto, Masakazu, Shimizu, Kyoko, Shibata, Noriyuki, Shiratori, Keiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576306/
https://ncbi.nlm.nih.gov/pubmed/23227827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-88
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