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The Linear Interaction Energy Method for the Prediction of Protein Stability Changes Upon Mutation
The coupling of protein energetics and sequence changes is a critical aspect of computational protein design, as well as for the understanding of protein evolution, human disease, and drug resistance. In order to study the molecular basis for this coupling, computational tools must be sufficiently a...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240711/ https://ncbi.nlm.nih.gov/pubmed/22038697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23168 |
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