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NeEMO: a method using residue interaction networks to improve prediction of protein stability upon mutation

BACKGROUND: The rapid growth of un-annotated missense variants poses challenges requiring novel strategies for their interpretation. From the thermodynamic point of view, amino acid changes can lead to a change in the internal energy of a protein and induce structural rearrangements. This is of grea...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Giollo, Manuel, Martin, Alberto JM, Walsh, Ian, Ferrari, Carlo, Tosatto, Silvio CE
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083412/
https://ncbi.nlm.nih.gov/pubmed/25057121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S4-S7
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