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Design and Analysis of a Petri Net Model of the Von Hippel-Lindau (VHL) Tumor Suppressor Interaction Network

Von Hippel-Lindau (VHL) syndrome is a hereditary condition predisposing to the development of different cancer forms, related to germline inactivation of the homonymous tumor suppressor pVHL. The best characterized function of pVHL is the ubiquitination dependent degradation of Hypoxia Inducible Fac...

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Detalhes bibliográficos
Main Authors: Minervini, Giovanni, Panizzoni, Elisabetta, Giollo, Manuel, Masiero, Alessandro, Ferrari, Carlo, Tosatto, Silvio C. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041725/
https://ncbi.nlm.nih.gov/pubmed/24886840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096986
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