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Isoform-specific interactions of the von Hippel-Lindau tumor suppressor protein

Deregulation of the von Hippel-Lindau tumor suppressor protein (pVHL) is considered one of the main causes for malignant renal clear-cell carcinoma (ccRCC) insurgence. In human, pVHL exists in two isoforms, pVHL19 and pVHL30 respectively, displaying comparable tumor suppressor abilities. Mutations o...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Minervini, Giovanni, Mazzotta, Gabriella M., Masiero, Alessandro, Sartori, Elena, Corrà, Samantha, Potenza, Emilio, Costa, Rodolfo, Tosatto, Silvio C. E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515828/
https://ncbi.nlm.nih.gov/pubmed/26211615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12605
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