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Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site
Structural results with minor groove binding agents, such as netropsin, have provided detailed, atomic level views of DNA molecular recognition. Solution studies, however, indicate that there is complexity in the binding of minor groove agents to a single site. Netropsin, for example, has two DNA bi...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3239193/ https://ncbi.nlm.nih.gov/pubmed/21890907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr699 |
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