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Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
In mammalian cells, the main pathway for DNA double-strand breaks (DSBs) repair is classical non-homologous end joining (C-NHEJ). An alternative or back-up NHEJ (B-NHEJ) pathway has emerged which operates preferentially under C-NHEJ defective conditions. Although B-NHEJ appears particularly relevant...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3239177/ https://ncbi.nlm.nih.gov/pubmed/21880593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr656 |
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