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Simplified RNA secondary structure mapping by automation of SHAPE data analysis
SHAPE (Selective 2′-hydroxyl acylation analysed by primer extension) technology has emerged as one of the leading methods of determining RNA secondary structure at the nucleotide level. A significant bottleneck in using SHAPE is the complex and time-consuming data processing that is required. We pre...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3239176/ https://ncbi.nlm.nih.gov/pubmed/21965531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr773 |
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