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Simplified RNA secondary structure mapping by automation of SHAPE data analysis

SHAPE (Selective 2′-hydroxyl acylation analysed by primer extension) technology has emerged as one of the leading methods of determining RNA secondary structure at the nucleotide level. A significant bottleneck in using SHAPE is the complex and time-consuming data processing that is required. We pre...

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Detalhes bibliográficos
Main Authors: Pang, Phillip S., Elazar, Menashe, Pham, Edward A., Glenn, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239176/
https://ncbi.nlm.nih.gov/pubmed/21965531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr773
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