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Mapping RNA–capsid interactions and RNA secondary structure within virus particles using next-generation sequencing
To characterize RNA–capsid binding sites genome-wide within mature RNA virus particles, we have developed a Next-Generation Sequencing (NGS) platform: viral Photo-Activatable Ribonucleoside CrossLinking (vPAR-CL). In vPAR-CL, 4-thiouridine is incorporated into the encapsidated genomes of virus parti...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6954446/ https://ncbi.nlm.nih.gov/pubmed/31799606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1124 |
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