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Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist.
3S(-)-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4- benzodiazepine-3-yl)-1H-indole-2-carboxamide (L-364,718) interacted in a competitive manner with rat pancreatic cholecystokinin (CCK) receptors as determined by Scatchard analysis of the specific binding of 125I-labeled CCK. The affinity of L-364,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4923 |
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