Single-cell dissection of transcriptional heterogeneity in human colon tumors

Cancer is often viewed as a caricature of normal developmental processes, but the extent by which its cellular heterogeneity truly recapitulates multi-lineage differentiation processes of normal tissues remains unknown. Here, we implement “single-cell PCR gene-expression analysis” (SINCE-PCR) to dis...

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Bibliografski detalji
Glavni autori: Dalerba, Piero, Kalisky, Tomer, Sahoo, Debashis, Rajendran, Pradeep S., Rothenberg, Michael E., Leyrat, Anne A., Sim, Sopheak, Okamoto, Jennifer, Johnston, Darius M., Qian, Dalong, Zabala, Maider, Bueno, Janet, Neff, Norma F., Wang, Jianbin, Shelton, Andrew A., Visser, Brendan, Hisamori, Shigeo, Shimono, Yohei, van de Wetering, Marc, Clevers, Hans, Clarke, Michael F., Quake, Stephen R.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237928/
https://ncbi.nlm.nih.gov/pubmed/22081019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2038
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