Single-cell dissection of transcriptional heterogeneity in human colon tumors

Cancer is often viewed as a caricature of normal developmental processes, but the extent by which its cellular heterogeneity truly recapitulates multi-lineage differentiation processes of normal tissues remains unknown. Here, we implement “single-cell PCR gene-expression analysis” (SINCE-PCR) to dis...

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Detaylı Bibliyografya
Asıl Yazarlar: Dalerba, Piero, Kalisky, Tomer, Sahoo, Debashis, Rajendran, Pradeep S., Rothenberg, Michael E., Leyrat, Anne A., Sim, Sopheak, Okamoto, Jennifer, Johnston, Darius M., Qian, Dalong, Zabala, Maider, Bueno, Janet, Neff, Norma F., Wang, Jianbin, Shelton, Andrew A., Visser, Brendan, Hisamori, Shigeo, Shimono, Yohei, van de Wetering, Marc, Clevers, Hans, Clarke, Michael F., Quake, Stephen R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237928/
https://ncbi.nlm.nih.gov/pubmed/22081019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2038
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