Identification of a cKit(+) Colonic Crypt Base Secretory Cell That Supports Lgr5(+) Stem Cells in Mice

BACKGROUND & AIMS: Paneth cells contribute to the small intestinal niche of Lgr5(+) stem cells. Although the colon also contains Lgr5(+) stem cells, it does not contain Paneth cells. We investigated the existence of colonic Paneth-like cells that have a distinct transcriptional signature and sup...

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Detalhes bibliográficos
Main Authors: Rothenberg, Michael E., Nusse, Ysbrand, Kalisky, Tomer, Lee, John J., Dalerba, Piero, Scheeren, Ferenc, Lobo, Neethan, Kulkarni, Subhash, Sim, Sopheak, Qian, Dalong, Beachy, Philip A., Pasricha, Pankaj J., Quake, Stephen R., Clarke, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911891/
https://ncbi.nlm.nih.gov/pubmed/22333952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.02.006
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