Identification of a cKit(+) Colonic Crypt Base Secretory Cell That Supports Lgr5(+) Stem Cells in Mice

BACKGROUND & AIMS: Paneth cells contribute to the small intestinal niche of Lgr5(+) stem cells. Although the colon also contains Lgr5(+) stem cells, it does not contain Paneth cells. We investigated the existence of colonic Paneth-like cells that have a distinct transcriptional signature and sup...

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Hlavní autoři: Rothenberg, Michael E., Nusse, Ysbrand, Kalisky, Tomer, Lee, John J., Dalerba, Piero, Scheeren, Ferenc, Lobo, Neethan, Kulkarni, Subhash, Sim, Sopheak, Qian, Dalong, Beachy, Philip A., Pasricha, Pankaj J., Quake, Stephen R., Clarke, Michael F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911891/
https://ncbi.nlm.nih.gov/pubmed/22333952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.02.006
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