Flanking Nucleotide Specificity for DNA Mismatch Repair-Deficient Frameshifts within Activin Receptor 2 (ACVR2)

We previously demonstrated that exonic selectivity for frameshift mutation (exon 10 over exon 3) of ACVR2 in mismatch repair (MMR)-deficient cells is partially determined by 6 nucleotides flanking 5’ and 3’ of each microsatellite. Substitution of flanking nucleotides surrounding the exon 10 microsat...

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Hlavní autoři: Chung, Heekyung, Chaudhry, Joy, Lai, Jenny F., Young, Dennis J., Carethers, John M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237829/
https://ncbi.nlm.nih.gov/pubmed/22001236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.09.009
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