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Both microsatellite length and sequence context determine frameshift mutation rates in defective DNA mismatch repair
It is generally accepted that longer microsatellites mutate more frequently in defective DNA mismatch repair (MMR) than shorter microsatellites. Indeed, we have previously observed that the A(10) microsatellite of transforming growth factor beta type II receptor (TGFBR2) frameshifts −1 bp at a faste...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912546/ https://ncbi.nlm.nih.gov/pubmed/20418486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq151 |
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