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Defective Mismatch Repair, Microsatellite Mutation Bias, and Variability in Clinical Cancer Phenotypes

Microsatellite instability (MSI) is associated with 10–15% of colorectal, endometrial, ovarian and gastric cancers, and has long been used as a diagnostic tool for hereditary nonpolyposis colorectal carcinoma-related cancers. Tumor specific length alterations within microsatellites are generally acc...

詳細記述

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書誌詳細
主要な著者: Shah, Sandeep N., Hile, Suzanne E., Eckert, Kristin A.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807994/
https://ncbi.nlm.nih.gov/pubmed/20068152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3049
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