Cyclin E and histone H3 levels are regulated by 5-fluorouracil in a DNA mismatch repair-dependent manner

Several studies indicate that the DNA mismatch repair (MMR) system may trigger cytotoxicity upon 5-fluorouracil (5-FU) recognition, but signaling pathways regulated by MMR in response to 5-FU are unknown. We hypothesize that recognition of 5-FU in DNA by MMR proteins trigger specific signaling casca...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chung, Heekyung, Chaudhry, Joy, Lopez, Claudia G, Carethers, John M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2010
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230292/
https://ncbi.nlm.nih.gov/pubmed/20930505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.11.13447
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