טוען...
Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
Diabetic nephropathy (DN) is the major life-threatening complication of diabetes. Abnormal permselectivity of glomerular basement membrane (GBM) plays an important role in DN pathogenesis. Heparanase is the predominant enzyme that degrades heparan sulfate (HS), the main polysaccharide of the GBM. Lo...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Diabetes Association
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237641/ https://ncbi.nlm.nih.gov/pubmed/22106160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1024 |
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