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Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice
Heparanase is the sole mammalian endoglycosidase that selectively degrades heparan sulfate, the key polysaccharide associated with the cell surface and extracellular matrix of a wide range of tissues. Extensively studied for its capacity to promote cancer progression, heparanase enzyme was recently...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Basel
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059205/ https://ncbi.nlm.nih.gov/pubmed/24169805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1496-9 |
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