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Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice

Heparanase is the sole mammalian endoglycosidase that selectively degrades heparan sulfate, the key polysaccharide associated with the cell surface and extracellular matrix of a wide range of tissues. Extensively studied for its capacity to promote cancer progression, heparanase enzyme was recently...

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Main Authors: Lerner, Immanuel, Zcharia, Eyal, Neuman, Tzahi, Hermano, Esther, Rubinstein, Ariel M., Vlodavsky, Israel, Elkin, Michael
Format: Artigo
Jezik:Inglês
Izdano: Springer Basel 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059205/
https://ncbi.nlm.nih.gov/pubmed/24169805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1496-9
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