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Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice

Heparanase is the sole mammalian endoglycosidase that selectively degrades heparan sulfate, the key polysaccharide associated with the cell surface and extracellular matrix of a wide range of tissues. Extensively studied for its capacity to promote cancer progression, heparanase enzyme was recently...

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Detalhes bibliográficos
Main Authors: Lerner, Immanuel, Zcharia, Eyal, Neuman, Tzahi, Hermano, Esther, Rubinstein, Ariel M., Vlodavsky, Israel, Elkin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059205/
https://ncbi.nlm.nih.gov/pubmed/24169805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1496-9
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