Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is closely associated with colon cancer. Expression of the enzyme heparanase is clearly linked to colon carcinoma progression, but its role in UC is unknown. Here we demonstrate for what we believe to be the first time the importan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lerner, Immanuel, Hermano, Esther, Zcharia, Eyal, Rodkin, Dina, Bulvik, Raanan, Doviner, Victoria, Rubinstein, Ariel M., Ishai-Michaeli, Rivka, Atzmon, Ruth, Sherman, Yoav, Meirovitz, Amichay, Peretz, Tamar, Vlodavsky, Israel, Elkin, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083784/
https://ncbi.nlm.nih.gov/pubmed/21490396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43792
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