Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is closely associated with colon cancer. Expression of the enzyme heparanase is clearly linked to colon carcinoma progression, but its role in UC is unknown. Here we demonstrate for what we believe to be the first time the importan...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lerner, Immanuel, Hermano, Esther, Zcharia, Eyal, Rodkin, Dina, Bulvik, Raanan, Doviner, Victoria, Rubinstein, Ariel M., Ishai-Michaeli, Rivka, Atzmon, Ruth, Sherman, Yoav, Meirovitz, Amichay, Peretz, Tamar, Vlodavsky, Israel, Elkin, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083784/
https://ncbi.nlm.nih.gov/pubmed/21490396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43792
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky