Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is closely associated with colon cancer. Expression of the enzyme heparanase is clearly linked to colon carcinoma progression, but its role in UC is unknown. Here we demonstrate for what we believe to be the first time the importan...

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Bibliografiset tiedot
Päätekijät: Lerner, Immanuel, Hermano, Esther, Zcharia, Eyal, Rodkin, Dina, Bulvik, Raanan, Doviner, Victoria, Rubinstein, Ariel M., Ishai-Michaeli, Rivka, Atzmon, Ruth, Sherman, Yoav, Meirovitz, Amichay, Peretz, Tamar, Vlodavsky, Israel, Elkin, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083784/
https://ncbi.nlm.nih.gov/pubmed/21490396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43792
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