Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.

The consistent cytogenetic translocation of chronic myelogenous leukemia (the Philadelphia chromosome, Ph1) has been observed in cells of multiple hematopoietic lineages. This translocation creates a chimeric gene composed of breakpoint-cluster-region (bcr) sequences from chromosome 22 fused to a po...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Konopka, J B, Clark, S, McLaughlin, J, Nitta, M, Kato, Y, Strife, A, Clarkson, B, Witte, O N
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1986
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4049
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