Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.

The consistent cytogenetic translocation of chronic myelogenous leukemia (the Philadelphia chromosome, Ph1) has been observed in cells of multiple hematopoietic lineages. This translocation creates a chimeric gene composed of breakpoint-cluster-region (bcr) sequences from chromosome 22 fused to a po...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Konopka, J B, Clark, S, McLaughlin, J, Nitta, M, Kato, Y, Strife, A, Clarkson, B, Witte, O N
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1986
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4049
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