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Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.

The Philadelphia chromosome (t9:22;q34:q11) is found in more than 90% of patients with chronic myelogenous leukemia, in 10 to 20% of patients with acute lymphocytic leukemia, and in 1 to 2% of patients with acute myelogenous leukemia. Alternative chimeric oncogenes are formed by splicing different s...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: McLaughlin, J, Chianese, E, Witte, O N
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2747638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.5.1866
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