Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.

Ítems similars

• Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.
  per: McLaughlin, J, et al.
  Publicat: (1989)
• Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.
  per: Kelliher, M A, et al.
  Publicat: (1990)
• In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome.
  per: McLaughlin, J, et al.
  Publicat: (1987)
• BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.
  per: Muller, A J, et al.
  Publicat: (1991)
• The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
  per: Lugo, T G, et al.
  Publicat: (1989)