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Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.

Two forms of activated BCR/ABL proteins, P210 and P185, that differ in BCR-derived sequences, are associated with Philadelphia chromosome-positive leukemias. One of these diseases is chronic myelogenous leukemia, an indolent disease arising in hematopoietic stem cells that is almost always associate...

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Udgivet i:Mol Cell Biol
Principais autores: Kelliher, M, Knott, A, McLaughlin, J, Witte, O N, Rosenberg, N
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1875948/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.9.4710-4716.1991
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