Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.
Two forms of activated BCR/ABL proteins, P210 and P185, that differ in BCR-derived sequences, are associated with Philadelphia chromosome-positive leukemias. One of these diseases is chronic myelogenous leukemia, an indolent disease arising in hematopoietic stem cells that is almost always associate...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1991
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361365/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1875948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.9.4710-4716.1991 |
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