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Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.

The consistent cytogenetic translocation of chronic myelogenous leukemia (the Philadelphia chromosome, Ph1) has been observed in cells of multiple hematopoietic lineages. This translocation creates a chimeric gene composed of breakpoint-cluster-region (bcr) sequences from chromosome 22 fused to a po...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Konopka, J B, Clark, S, McLaughlin, J, Nitta, M, Kato, Y, Strife, A, Clarkson, B, Witte, O N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1986
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4049
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