Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.

The consistent cytogenetic translocation of chronic myelogenous leukemia (the Philadelphia chromosome, Ph1) has been observed in cells of multiple hematopoietic lineages. This translocation creates a chimeric gene composed of breakpoint-cluster-region (bcr) sequences from chromosome 22 fused to a po...

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Detalhes bibliográficos
Main Authors: Konopka, J B, Clark, S, McLaughlin, J, Nitta, M, Kato, Y, Strife, A, Clarkson, B, Witte, O N
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323663/
https://ncbi.nlm.nih.gov/pubmed/3012546
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