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Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion
Trans-SNARE complexes catalyze fast synaptic vesicle fusion and bind complexin, but the function of complexin binding to SNARE complexes remains unclear. Here we show that in neuronal synapses, complexin simultaneously suppressed spontaneous fusion and activated fast Ca(2+)-evoked fusion. The dual f...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235366/ https://ncbi.nlm.nih.gov/pubmed/19164751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166505 |
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