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Distinct Domains of Complexins Bind SNARE Complexes and Clamp Fusion in Vitro

In regulated exocytosis, the core membrane fusion machinery proteins, the SNARE proteins, are assisted by a group of regulatory factors in order to couple membrane fusion to an increase of intracellular calcium ion (Ca(2+)) concentration. Complexin-I and synaptotagmin-I have been shown to be key ele...

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Bibliografiske detaljer
Main Authors: Giraudo, Claudio G., Garcia-Diaz, Alejandro, Eng, William S., Yamamoto, Ai, Melia, Thomas J., Rothman, James E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475712/
https://ncbi.nlm.nih.gov/pubmed/18499660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803478200
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