Interaction of the Complexin Accessory Helix with the C-Terminus of the SNARE Complex: Molecular-Dynamics Model of the Fusion Clamp

SNARE complexes form between the synaptic vesicle protein synaptobrevin and the plasma membrane proteins syntaxin and SNAP25 to drive membrane fusion. A cytosolic protein, complexin (Cpx), binds to the SNARE bundle, and its accessory helix (AH) functions to clamp synaptic vesicle fusion. We performe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bykhovskaia, Maria, Jagota, Anand, Gonzalez, Agustin, Vasin, Alexander, Littleton, J. Troy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2013
Gaiak:
Membrane
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736676/
https://ncbi.nlm.nih.gov/pubmed/23931316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.018
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