Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo

Complexin (Cpx) is a SNARE-binding protein that regulates neurotransmission by clamping spontaneous synaptic vesicle fusion in the absence of Ca(2+) influx while promoting evoked release in response to an action potential. Previous studies indicated Cpx may cross-link multiple SNARE complexes via a...

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Main Authors: Cho, Richard W., Kümmel, Daniel, Li, Feng, Baguley, Stephanie Wood, Coleman, Jeff, Rothman, James E., Littleton, J. Troy
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104896/
https://ncbi.nlm.nih.gov/pubmed/24982161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409311111
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