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Accessory α-helix of complexin I can displace VAMP2 locally in the complexin-SNARE quaternary complex
The calcium-triggered neurotransmitter release requires three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins: synaptobrevin 2 (or VAMP2) on the synaptic vesicle and syntaxin 1 and SNAP-25 at the presynaptic plasmas membrane. This minimal fusion machinery is be...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822017/ https://ncbi.nlm.nih.gov/pubmed/20026076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.020 |
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