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The accessory helix of complexin functions by stabilizing central helix secondary structure

The presynaptic protein complexin (CPX) is a critical regulator of synaptic vesicle fusion, but the mechanisms underlying its regulatory effects are not well understood. Its highly conserved central helix (CH) directly binds the ternary SNARE complex and is required for all known CPX functions. The...

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Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Radoff, Daniel T, Dong, Yongming, Snead, David, Bai, Jihong, Eliezer, David, Dittman, Jeremy S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270070/
https://ncbi.nlm.nih.gov/pubmed/25383924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04553
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